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Cardiovascular Health

Cardiovascular Health sits under Chronic Condition Management . Heart and vascular disease: risk, diagnosis, and the evidence behind treatment.

8 stories

Lp(a) Drug Failure: Why Pelacarsen Didn’t Work and What’s Next
Cardiology

Lp(a) Drug Failure: Why Pelacarsen Didn’t Work and What’s Next

Novartis discontinues pelacarsen after Phase 3 trial showed no cardiovascular benefit. Learn why this Lp(a)-lowering drug failed and what novel RNA therapies are coming next.

Dr. Amrita S. Pai, PharmD Sep 14, 2026 3 min read
One-Time Gene Editing Cut LDL Cholesterol in Half for a Year — and It's Not a Pill
Cardiovascular Health

One-Time Gene Editing Cut LDL Cholesterol in Half for a Year — and It's Not a Pill

A small CRISPR Therapeutics trial dropped LDL by roughly 50 percent with a single infusion, and the effect held for a full year. Here is how in-body gene editing differs from statins, enlicitide, and inclisiran, who could qualify, and what the long-term unknowns are.

Dr. Helena Vasquez, MD Sep 2, 2026 7 min read
Why Your New Blood Thinner Doesn't Need Monitoring Like Warfarin Did
Cardiovascular Health

Why Your New Blood Thinner Doesn't Need Monitoring Like Warfarin Did

Direct oral anticoagulants (DOACs) replaced warfarin for many people with atrial fibrillation. We explain why DOACs need less monitoring, how they compare on stroke and bleeding, and who still needs warfarin.

Dr. Alan Reyes, PharmD Aug 27, 2026 5 min read
Your Home Blood Pressure Cuff Might Be Lying to You: 2026 Measurement Fixes
Cardiovascular Health

Your Home Blood Pressure Cuff Might Be Lying to You: 2026 Measurement Fixes

Inconsistent home BP readings often trace to device choice and technique, not your health. Here is how to pick a validated cuff and measure like a clinician.

Marcus Lindqvist, PharmD Aug 21, 2026 3 min read
The First Daily Cholesterol Pill That Beats Statins and Skips the Needle Just Got Approved
Cardiovascular Health

The First Daily Cholesterol Pill That Beats Statins and Skips the Needle Just Got Approved

Enlicitide (Lipfendra), the first oral PCSK9 inhibitor, won FDA approval in July 2026 and cuts LDL by more than half. Here is who it helps and how it fits with statins.

Samuel Okafor, MD Aug 11, 2026 5 min read
The 2026 Cholesterol Rules Just Added a Test Most Adults Never Had: Lp(a)
Cardiovascular Health

The 2026 Cholesterol Rules Just Added a Test Most Adults Never Had: Lp(a)

The 2026 ACC/AHA dyslipidemia guideline says every adult should be tested once for Lp(a), adds ApoB and 30-year risk, and brings back specific LDL targets. Here is what the changes mean for you.

Samuel Okafor, MD Aug 11, 2026 5 min read
Cholesterol Screening Starts at 19 Now: 2026 ACC/AHA Guideline Overhaul
Cardiovascular Health

Cholesterol Screening Starts at 19 Now: 2026 ACC/AHA Guideline Overhaul

The 2026 ACC/AHA dyslipidemia guideline replaces the 2018 recommendations with earlier screening, new PREVENT risk equations, universal Lp(a) testing, and lower LDL-C targets for many patients.

Dr. Helena Vasquez, MD Jul 31, 2026 4 min read
CKM Syndrome: What the First-Ever 2026 AHA/ACC Guideline Means for You
Cardiovascular Health

CKM Syndrome: What the First-Ever 2026 AHA/ACC Guideline Means for You

The AHA and ACC issued the first clinical guideline for cardiovascular-kidney-metabolic syndrome in June 2026. Here is what the four-stage system means for your care.

Dr. Helena Vasquez, MD Jul 31, 2026 4 min read

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